Antibody Information
General Information of This Antibody
| Antibody ID | ANI0CHHHX |
|||||
|---|---|---|---|---|---|---|
| Antibody Name | Targeted against E. coli mAb (hWN1) |
|||||
| Antibody Type | Monoclonal antibody (mAb) |
|||||
| Antibody Subtype | Humanized IgG |
|||||
| Antigen Name | Undisclosed |
Antigen Info | ||||
Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
ABC-1C [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
10.00 nM
|
|||
| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
|
||||
| In Vitro Model | . | Escherichia coli 2 (E. coli 2) | . | ||
| Experiment 2 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
130 nM
|
|||
| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
|
||||
| In Vitro Model | . | Escherichia coli 1 (E. coli 1) | . | ||
ABC-3C [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
40.00 nM
|
|||
| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
|
||||
| In Vitro Model | . | Escherichia coli 2 (E. coli 2) | . | ||
| Experiment 2 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
170 nM
|
|||
| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
|
||||
| In Vitro Model | . | Escherichia coli 1 (E. coli 1) | . | ||
ABC-3E [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) | > 1000 nM | |||
| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
|
||||
| In Vitro Model | . | Escherichia coli 1 (E. coli 1) | . | ||
| Experiment 2 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) | > 1000 nM | |||
| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
|
||||
| In Vitro Model | . | Escherichia coli 2 (E. coli 2) | . | ||
ABC-2A [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
1000 nM
|
|||
| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
|
||||
| In Vitro Model | . | Escherichia coli 1 (E. coli 1) | . | ||
| Experiment 2 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
1000 nM
|
|||
| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
|
||||
| In Vitro Model | . | Escherichia coli 2 (E. coli 2) | . | ||
References