Antibody Information
General Information of This Antibody (ID: ANI0CHHHX)
| Antibody Name | Targeted against E. coli mAb (hWN1) |
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| Antibody Type | Monoclonal antibody (mAb) |
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| Antibody Subtype | Humanized IgG |
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| Antigen Name | Undisclosed |
Antigen Info | ||||
| Click to Show/Hide the Sequence Information of This Antibody | ||||||
Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
ABC-1C [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
10 nM
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| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
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| In Vitro Model | . | Escherichia coli 2 (E. coli 2) | . | ||
| Experiment 2 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
130 nM
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| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
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| In Vitro Model | . | Escherichia coli 1 (E. coli 1) | . | ||
ABC-3C [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
40 nM
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| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
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| In Vitro Model | . | Escherichia coli 2 (E. coli 2) | . | ||
| Experiment 2 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
170 nM
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| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
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| In Vitro Model | . | Escherichia coli 1 (E. coli 1) | . | ||
ABC-3E [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) | > 1000 nM | |||
| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
|
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| In Vitro Model | . | Escherichia coli 2 (E. coli 2) | . | ||
| Experiment 2 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) | > 1000 nM | |||
| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
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| In Vitro Model | . | Escherichia coli 1 (E. coli 1) | . | ||
ABC-2A [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
1000 nM
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| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
|
||||
| In Vitro Model | . | Escherichia coli 2 (E. coli 2) | . | ||
| Experiment 2 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
1000 nM
|
|||
| Method Description |
Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
|
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| In Vitro Model | . | Escherichia coli 1 (E. coli 1) | . | ||
References