Antibody ID	ANI0CHHHX
Antibody Name	Targeted against E. coli mAb (hWN1)
Antibody Type	Monoclonal antibody (mAb)
Antibody Subtype	Humanized IgG
Antigen Name	.					Antigen Info

Experiment 1 Reporting the Activity Date of This ADC					[1]
Efficacy Data	Half Maximal Effective Concentration (EC50)	10.00 nM
Method Description	Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
In Vitro Model	.	Escherichia coli 2 (E. coli 2)		.
Experiment 2 Reporting the Activity Date of This ADC					[1]
Efficacy Data	Half Maximal Effective Concentration (EC50)	130 nM
Method Description	Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
In Vitro Model	.	Escherichia coli 1 (E. coli 1)		.

Experiment 1 Reporting the Activity Date of This ADC					[1]
Efficacy Data	Half Maximal Effective Concentration (EC50)	40.00 nM
Method Description	Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
In Vitro Model	.	Escherichia coli 2 (E. coli 2)		.
Experiment 2 Reporting the Activity Date of This ADC					[1]
Efficacy Data	Half Maximal Effective Concentration (EC50)	170 nM
Method Description	Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
In Vitro Model	.	Escherichia coli 1 (E. coli 1)		.

Experiment 1 Reporting the Activity Date of This ADC					[1]
Efficacy Data	Half Maximal Effective Concentration (EC50)	> 1000 nM
Method Description	Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
In Vitro Model	.	Escherichia coli 1 (E. coli 1)		.
Experiment 2 Reporting the Activity Date of This ADC					[1]
Efficacy Data	Half Maximal Effective Concentration (EC50)	> 1000 nM
Method Description	Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
In Vitro Model	.	Escherichia coli 2 (E. coli 2)		.

Experiment 1 Reporting the Activity Date of This ADC					[1]
Efficacy Data	Half Maximal Effective Concentration (EC50)	1000 nM
Method Description	Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
In Vitro Model	.	Escherichia coli 1 (E. coli 1)		.
Experiment 2 Reporting the Activity Date of This ADC					[1]
Efficacy Data	Half Maximal Effective Concentration (EC50)	1000 nM
Method Description	Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
In Vitro Model	.	Escherichia coli 2 (E. coli 2)		.

Ref 1	Antibody-Bactericidal Macrocyclic Peptide Conjugates To Target Gram-Negative Bacteria. Chembiochem. 2018 Oct 4;19(19):2039-2044. doi: 10.1002/cbic.201800295. Epub 2018 Sep 14.