Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0YKWSC
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| ADC Name |
huB12-DM1
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| Synonyms |
huB12-DM1
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| Organization |
University of Wisconsin School of Medicine and Public Health.; University of Minnesota School of Medicine.; University of Wisconsin Carbone Cancer Center.; William S Middleton Memorial Veterans' Hospital.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
4
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| Antibody Name |
huB12
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Antibody Info | ||||
| Antigen Name |
Prolyl endopeptidase FAP (FAP)
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Antigen Info | ||||
| Payload Name |
Mertansine DM1
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Random conjugation through nucleophilic lysines
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