Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ID: DRG0YKESR)
| ADC Name |
ACR246
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| Synonyms |
ACR246; ADC2154
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| Organization |
Accurus Biosciences (Originator)
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| Drug Status |
Phase 1/2
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| Drug-to-Antibody Ratio |
8
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| Antibody Name |
Anti-5T4 humanized mAb
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Antibody Info | ||||
| Antigen Name |
Trophoblast glycoprotein (TPBG)
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Antigen Info | ||||
| Payload Name |
D-2102
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Payload Info | ||||
| Payload Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
A cleavable linker
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Linker Info | ||||
| Conjugate Type |
Site-specific
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2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
| Disease Name | Phase 1 | Phase 2 | Phase 3 | Approved |
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| Oesophageal cancer | ||||
| Colorectal cancer | ||||
| Lung cancer | ||||
| Ovarian cancer | ||||
| Prostate cancer | ||||
| Unspecific solid tumor |