Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ID: DRG0YBSML)
| ADC Name |
AK146D1
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| Synonyms |
AK146D1
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| Organization |
Akeso (Originator)
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| Drug Status |
Phase 1
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| Structure |
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| Antibody Name |
Anti-nectin-4/TROP2 bsAb
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Antibody Info | ||||
| Antigen Name |
Nectin-4 (NECTIN4); Tumor-associated calcium signal transducer 2 (TACSTD2)
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Antigen Info | ||||
| Payload Name |
DXd
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Payload Info | ||||
| Payload Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Mc-Ala-Ala-Ala
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Linker Info | ||||
| Conjugate Type |
Random Cysteines
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2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
| Indication | Phase 1 | Phase 2 | Phase 3 | Approved | |||
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| Unspecific solid tumor |
2 Trials
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