Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0XWJRC
|
|||||
|---|---|---|---|---|---|---|
| ADC Name |
Non-binding IgG -ADC
|
|||||
| Synonyms |
Non-binding IgG -ADC
Click to Show/Hide
|
|||||
| Organization |
Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
|
|||||
| Drug Status |
Investigative
|
|||||
| Drug-to-Antibody Ratio |
3
|
|||||
| Structure |
|
|||||
| Antibody Name |
Control mouse IgG
|
Antibody Info | Antigen Name |
Undisclosed
|
||
| Payload Name |
Monomethyl auristatin E
|
Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
|
Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
|
Linker Info | ||||
| Conjugate Type |
Site-specific conjugation via newly installed N-linked glycosylation sites
|
|||||
| Combination Type |
Vedotin
|
|||||