Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0XUKDO
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| ADC Name |
wO2024222841A1 ADC45
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| Synonyms |
ADC45
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| Organization |
CSPC MEGALITH BIOPHARMACEUTICAL CO.,LTD.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
7.9
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| Structure |
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| Antibody Name |
Trastuzumab
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
B63
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Payload Info | ||||
| Therapeutic Target |
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1)
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Target Info | ||||
| Linker Name |
OXDc-VA-PAB (PEG)
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
LD45
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