Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0XUIOR
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| ADC Name |
RC58-ADC-2
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| Synonyms |
RC58-ADC 2; RC58-ADC2
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| Organization |
RemeGen Co., Ltd.
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
B-cell lymphoma [ICD11:2A86]
Investigative
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| Drug-to-Antibody Ratio |
3.8
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| Structure |
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| Antibody Name |
RC58
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Antibody Info | ||||
| Antigen Name |
B-lymphocyte antigen CD19 (CD19)
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Antigen Info | ||||
| Payload Name |
Duostain 3
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Payload Info | ||||
| Linker Name |
Bis-bromine linker-PEG2-VC-PAB
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Linker Info | ||||
| Conjugate Type |
Reduction of inter-molecule chain disulfide bonds can produce free sulfhydryl groups which support the conjunction of antibody and drug at specific cysteine residues via maleimide-containing linkers.
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