Linker Information
General Information of This Linker
| Linker ID |
LIN0TTUBH
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|---|---|---|---|---|---|---|
| Linker Name |
Bis-bromine linker-PEG2-VC-PAB
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C36H48Br2N8O8
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| Isosmiles |
CC(C)C(NC(=O)CCOCCOCCNC(=O)c1ccc2nc(CBr)c(CBr)nc2c1)C(=O)NC(CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1
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| InChI |
InChI=1S/C36H48Br2N8O8/c1-22(2)32(35(51)45-27(4-3-12-41-36(39)52)34(50)42-25-8-5-23(21-47)6-9-25)46-31(48)11-14-53-16-17-54-15-13-40-33(49)24-7-10-26-28(18-24)44-30(20-38)29(19-37)43-26/h5-10,18,22,27,32,47H,3-4,11-17,19-21H2,1-2H3,(H,40,49)(H,42,50)(H,45,51)(H,46,48)(H3,39,41,52)
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| InChIKey |
ZRMPNECVZZTJJU-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
880.636
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Polar area
|
235.99
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Complexity
|
54
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xlogp Value
|
2.7778
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Heavy Count
|
54
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Rot Bonds
|
23
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Hbond acc
|
10
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker
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