Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0XRDLA
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| ADC Name |
S3F-CL-MMAE
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| Synonyms |
SIA-01; SIA-101; SIA-102; SIA-103; SIA-104; Anti-SialylTn mAbs (Siamab Therapeutics)
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| Organization |
Siamab Therapeutics, Inc.
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| Drug Status |
Clinical candidate
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| Indication |
In total 1 Indication(s)
Solid tumors [ICD11:2A00-2A0Z|2B50-2F9Z]
Clinical candidate
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| Structure |
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| Antibody Name |
Anti-sTn mAb S3F
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Antibody Info | ||||
| Antigen Name |
Onco-foetal sialyl-Tn
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
Vedotin
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