Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0XFYQA
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| ADC Name |
SMCC-calicheamicin-ADC
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| Synonyms |
SMCC-calicheamicin-ADC
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| Organization |
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
1-8
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| Antibody Name |
Trastuzumab
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
Calicheamicin
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Payload Info | ||||
| Linker Name |
Succinimidyl-4- (N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
SMCC-calicheamicin
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