Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0XDMVY
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|---|---|---|---|---|---|---|
| ADC Name |
T-Fc-Val-Cit-MMAE
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| Drug Status |
Investigative
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| Indication |
In total 5 Indication(s)
Breast ductal carcinoma [ICD11:2C61]
Investigative
Lung cancer [ICD11:2C25]
Investigative
Lung large cell carcinoma [ICD11:2C25]
Investigative
Lung squamous cell carcinoma [ICD11:2C25]
Investigative
Osteosarcoma [ICD11:2B51]
Investigative
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| Structure |
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| Antibody Name |
Human Anti-FGFR1 Fc
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Antibody Info | ||||
| Antigen Name |
Fibroblast growth factor receptor 1 (FGFR1)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
Vedotin
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