General Information of This Antibody-drug Conjugate (ID: DRG0VVKYV)
ADC Name
FZ-AD005
Synonyms
FZ-AD005; F0041
   Click to Show/Hide
Organization
Fudan-Zhangjiang Bio-Pharmaceutical (Originator)
Drug Status
Phase 1
Drug-to-Antibody Ratio
8
Structure
Antibody Name
Anti-DLL3 antibody
 Antibody Info 
Antigen Name
Delta-like protein 3 (DLL3)
 Antigen Info 
Payload Name
DXd
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
Mc-Val-Ala-PABC double self-immolative linker
 Linker Info 
Conjugate Type
Random Cysteines
Combination Type
BB05
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Disease Name Phase 1 Phase 2 Phase 3 Approved
Brain cancer
1 Trials
Clinical trial identifier
NCT07455045
Lung cancer
1 Trials
Clinical trial identifier
NCT06424665; CTR20241732
Unspecific solid tumor
1 Trials
Clinical trial identifier
NCT06424665; CTR20241732