Antibody-drug Conjugate Information

General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0UNGUT
ADC Name
EV20/NMS-P945
Synonyms
EV20-NMS-P945; EV20 NMS-P945
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Organization
University of Chieti-Pescara
Drug Status
Investigative
Indication
In total 6 Indication(s)
Gastric cancer
Clinical candidate
.
Head and neck cancer
Clinical candidate
.
Melanoma
Clinical candidate
.
Ovarian cancer
Clinical candidate
.
Pancreatic cancer
Clinical candidate
.
Prostate cancer
Clinical candidate
.
Drug-to-Antibody Ratio
3.6
Antibody Name
EV20
  Antibody Info 
Antigen Name
Receptor tyrosine-protein kinase erbB-3 (HER3)
  Antigen Info 
Payload Name
NMS-P528
  Payload Info 
Therapeutic Target
Human Deoxyribonucleic acid (hDNA)
  Target Info 
Linker Name
Cathepsin-cleavable peptidic linker with self-immolating spacer
  Linker Info 
Combination Type
NMS-P945