Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0UEPUJ
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| ADC Name |
h3/F11-Var16 (Anti-PSMA)-30.2867
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| Synonyms |
h3/F11-Var16(Anti-PSMA) 30.2867
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| Organization |
Heidelberg Pharma Research GmbH
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Prostate cancer [ICD11:2C82]
Investigative
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| Drug-to-Antibody Ratio |
2
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| Antibody Name |
Anti-PSMA mAb h3/F11-Var16
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Antibody Info | ||||
| Antigen Name |
Glutamate carboxypeptidase 2 (FOLH1)
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Antigen Info | ||||
| Payload Name |
Amanitin 30.2867
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Payload Info | ||||
| Therapeutic Target |
DNA-directed RNA polymerase II subunit RPB2 (POLR2B); DNA-directed RNA polymerase III subunit RPC7 (POLR3G)
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Target Info | ||||
| Linker Name |
Maleimido-caproyl
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Linker Info | ||||
| Conjugate Type |
Site-specific conjugation through the engineered cysteine (THIOMAB).
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