Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ID: DRG0TOHWK)
| ADC Name |
T-N-F (DAR 3.2)
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| Synonyms |
T-N-F DAR 3.2
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
3.2
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| Structure |
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| Antibody Name |
Trastuzumab
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (HER2)
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Antigen Info | ||||
| Payload Name |
Aldehyde-tagged MMAF
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Payload Info | ||||
| Payload Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Conjugate Type |
Conjugate synthesized via N-terminal conjugation method (NTERM) conjugation, conjugates cytotoxic drugs to the N-termini of an antibody through amine bond via reductive alkylation reaction.
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