Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0SWOJX
|
|||||
|---|---|---|---|---|---|---|
| ADC Name |
Anti-FGFR2/4 mAb-12438 SSNPP-DM3
|
|||||
| Synonyms |
Anti-FGFR2/4-mAb-12438-SSNPP-DM3
Click to Show/Hide
|
|||||
| Organization |
Novartis AG
|
|||||
| Drug Status |
Investigative
|
|||||
| Indication |
In total 3 Indication(s)
Breast cancer [ICD11:2C60-2C65]
Investigative
Colorectal cancer [ICD11:2B91]
Investigative
Gastric cancer [ICD11:2B72]
Investigative
|
|||||
| Drug-to-Antibody Ratio |
3-4
|
|||||
| Antibody Name |
Anti-FGFR2/4 mAb 12438
|
Antibody Info | ||||
| Antigen Name |
Fibroblast growth factor receptor 2 (FGFR2); Fibroblast growth factor receptor 4 (FGFR4)
|
Antigen Info | ||||
| Payload Name |
Maytansinoid DM3
|
Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
|
Target Info | ||||
| Linker Name |
Sulfosuccinimidyl-N-succinimidyl-4-(5-nitro-2-pyridyldithio) pentanoate (SSNPP)
|
Linker Info | ||||
If you find any error in data or bug in web service, please kindly report it to Dr. Shen et al.