General Information of This Antibody-drug Conjugate (ID: DRG0SMBYC)
ADC Name
MRG006
Synonyms
MRG006; MRG006A
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Organization
Miracogen (Originator)
Drug Status
Phase 2
Drug-to-Antibody Ratio
8
Antibody Name
Anti-GPC3 mAb
 Antibody Info 
Antigen Name
Glypican-3 (GPC3)
 Antigen Info 
Payload Name
Novel TOP1 inhibitor
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
MCC-AAQ
 Linker Info 
Conjugate Type
Random Cysteines
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Trial ID
NCT07093970; CTR20242454