General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0SAXJE
ADC Name
OMTX705
Synonyms
OMTX705; IN30705
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Organization
Oncomatryx (Originator);InxMed
Drug Status
Phase 1/2
Drug-to-Antibody Ratio
3.5
Structure
Antibody Name
OMTX005
 Antibody Info 
Antigen Name
Prolyl endopeptidase FAP (FAP)
 Antigen Info 
Payload Name
TAM470
 Payload Info 
Therapeutic Target
Microtubule (MT)
 Target Info 
Linker Name
Mc-Val-Cit-PABC-PEG3
 Linker Info 
Conjugate Type
Random Cysteines
The indication landscape of This ADC(2027 Update)
The clinical trial pipeline of This ADC(2027 Update)
Indication Phase 1 Phase 1/2 Phase 2 Phase 2/3 Phase 3 New Drug Application Approved
Breast cancer
1 Trials
Trial ID
NCT05547321; EUCT2025-521989-95-00; EUCT2024-514746-36-00
Colorectal cancer
1 Trials
Trial ID
NCT05547321; EUCT2025-521989-95-00; EUCT2024-514746-36-00
Gastric cancer
1 Trials
Trial ID
NCT05547321; EUCT2025-521989-95-00; EUCT2024-514746-36-00
Head and neck cancer
1 Trials
Trial ID
NCT05547321; EUCT2025-521989-95-00; EUCT2024-514746-36-00
Lung cancer
1 Trials
Trial ID
NCT05547321; EUCT2025-521989-95-00; EUCT2024-514746-36-00
Oesophageal cancer
1 Trials
Trial ID
NCT05547321; EUCT2025-521989-95-00; EUCT2024-514746-36-00
Ovarian cancer
1 Trials
Trial ID
NCT05547321; EUCT2025-521989-95-00; EUCT2024-514746-36-00
Peritoneal cancer
1 Trials
Trial ID
NCT05547321; EUCT2025-521989-95-00; EUCT2024-514746-36-00
Pleura mesothelioma
1 Trials
Trial ID
NCT05547321; EUCT2025-521989-95-00; EUCT2024-514746-36-00
Sarcomas
1 Trials
Trial ID
NCT05547321; EUCT2025-521989-95-00; EUCT2024-514746-36-00
Unspecific solid tumor
2 Trials
Trial ID
NCT05547321; EUCT2025-521989-95-00; EUCT2024-514746-36-00
TWCT00004042