General Information of This Antibody-drug Conjugate (ID: DRG0RRORA)
ADC Name
AK138D1
Synonyms
AK138D1
   Click to Show/Hide
Organization
Akeso (Originator)
Drug Status
Phase 1
Drug-to-Antibody Ratio
8
Structure
Antibody Name
Patritumab
 Antibody Info 
Antigen Name
Receptor tyrosine-protein kinase erbB-3 (HER3)
 Antigen Info 
Payload Name
DXd
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
Mc-Ala-Ala-Ala
 Linker Info 
Conjugate Type
Random Cysteines
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Disease Name Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
2 Trials
Clinical trial identifier
NCT06730386
NCT07281326; CTR20253795