General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0RONXP
ADC Name
sIM0609
Synonyms
SIM0609
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Organization
Simcere Pharmaceutical Group (Originator)
Drug Status
Phase 1
Drug-to-Antibody Ratio
8
Antibody Name
Anti-CDH17 antibody
 Antibody Info 
Antigen Name
Cadherin-17 (CDH17)
 Antigen Info 
Payload Name
CPT116
 Payload Info 
Therapeutic Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Undisclosed
The indication landscape of This ADC(2027 Update)
The clinical trial pipeline of This ADC(2027 Update)
Indication Phase 1 Phase 1/2 Phase 2 Phase 2/3 Phase 3 New Drug Application Approved
Colorectal cancer
1 Trials
Trial ID
NCT07265921; CTR20253903
Gastric cancer
1 Trials
Trial ID
NCT07265921; CTR20253903
Gastroesophageal junction adenocarcinoma
1 Trials
Trial ID
NCT07265921; CTR20253903
Pancreatic cancer
1 Trials
Trial ID
NCT07265921; CTR20253903
Unspecific solid tumor
1 Trials
Trial ID
NCT07265921; CTR20253903