Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0ORTCJ
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| ADC Name |
CN117337196A Compound54
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| Synonyms |
30kmPEG (SCAPDL1xSCACD47)-6 (Val-Cit-PAB-DEA-SN38)
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| Organization |
Shenzhen Enduring Biotech Ltd.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
1
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| Structure |
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| Antibody Name |
SCAPDL1xSCACD47
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Antibody Info | ||||
| Antigen Name |
Programmed cell death ligand 1 (PD-L1); Leukocyte surface antigen CD47 (CD47)
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Antigen Info | ||||
| Payload Name |
Active metabolite of irinotecan SN38
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
30kmPEG-6 (Val-Cit-PAB-DEA)
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
30kmPEG-Lys (Mal)- 6 (Val-Cit-PAB-DEA-SN38)
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