Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0OPJXS
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| ADC Name |
bMS-986490
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| Synonyms |
CEACAM5-TOPO1 ADC; CEACAM5-TOPO1 ADC (BMS); BMS-986490
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| Organization |
Bristol-Myers Squibb (Top20 MNC) (Originator)
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| Drug Status |
Phase 1/2
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| Antibody Name |
Anti-CEA antibody
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Antibody Info | ||||
| Antigen Name |
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5); Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6)
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Antigen Info | ||||
| Payload Name |
TOP1 inhibitor
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Conjugate Type |
Undisclosed
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The indication landscape of This ADC(2027 Update)
The clinical trial pipeline of This ADC(2027 Update)
| Indication | Phase 1 | Phase 1/2 | Phase 2 | Phase 2/3 | Phase 3 | New Drug Application | Approved | ||
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| Colorectal cancer |
1 Trials
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| Gastric cancer |
1 Trials
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| Lung cancer |
1 Trials
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| Unspecific solid tumor |
1 Trials
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