General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0MELRN
ADC Name
bC2027
Synonyms
BC2027
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Organization
BioCity Biopharmaceutics (Originator)
Drug Status
Phase 1
Antibody Name
Anti-GPC3 antibody
 Antibody Info 
Antigen Name
Glypican-3 (GPC3)
 Antigen Info 
Payload Name
TOP1 inhibitor
 Payload Info 
Therapeutic Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Undisclosed
The indication landscape of This ADC(2027 Update)
The clinical trial pipeline of This ADC(2027 Update)
Indication Phase 1 Phase 1/2 Phase 2 Phase 2/3 Phase 3 New Drug Application Approved
Liver cancer
1 Trials
Trial ID
NCT07368478; CTR20254151
Lung cancer
1 Trials
Trial ID
NCT07368478; CTR20254151
Oesophageal cancer
1 Trials
Trial ID
NCT07368478; CTR20254151
Ovarian cancer
1 Trials
Trial ID
NCT07368478; CTR20254151
Sarcomas
1 Trials
Trial ID
NCT07368478; CTR20254151
Unspecific solid tumor
1 Trials
Trial ID
NCT07368478; CTR20254151