General Information of This Antibody-drug Conjugate (ID: DRG0MELRN)
ADC Name
BC2027
Synonyms
BC2027
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Organization
BioCity Biopharmaceutics (Originator)
Drug Status
Phase 1
Antibody Name
Anti-GPC3 antibody
 Antibody Info 
Antigen Name
Glypican-3 (GPC3)
 Antigen Info 
Payload Name
TOP1 inhibitor
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Undisclosed
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Trial ID
NCT07368478; CTR20254151
Sarcoma
1 Trials
Trial ID
NCT07368478; CTR20254151
Oesophageal cancer
1 Trials
Trial ID
NCT07368478; CTR20254151
Liver cancer
1 Trials
Trial ID
NCT07368478; CTR20254151
Lung cancer
1 Trials
Trial ID
NCT07368478; CTR20254151
Ovarian cancer
1 Trials
Trial ID
NCT07368478; CTR20254151