General Information of This Antibody-drug Conjugate (ID: DRG0MBSAD)
ADC Name
VBC103
Synonyms
VBC103; VAC-103; AVZO-103
   Click to Show/Hide
Organization
VelaVigo (Originator);Avenzo Therapeutics
Drug Status
Phase 1/2
Antibody Name
Anti-Nectin-4/TROP2 bispecific VHH-Fc
 Antibody Info 
Antigen Name
Nectin-4 (NECTIN4); Tumor-associated calcium signal transducer 2 (TACSTD2)
 Antigen Info 
Payload Name
TOP1 inhibitor
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
Undisclosed
Conjugate Type
Undisclosed
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
2 Trials
Trial ID
NCT07193511
NCT07299747; CTR20254758
Urothelial cancer
1 Trials
Trial ID
NCT07193511