Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ID: DRG0LWKVS)
| ADC Name |
hMN-14-CL2A-SN-38
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| Synonyms |
hMN-14-CL2A-SN-38
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| Organization |
Immunomedics Inc
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
6.1
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| Structure |
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| Antibody Name |
hMN-14
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Antibody Info | ||||
| Antigen Name |
human leukocyte antigen-DR
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Antigen Info | ||||
| Payload Name |
Active metabolite of irinotecan SN38
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Payload Info | ||||
| Payload Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
CL2A
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
CL2A-SN-38
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