General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0LFZFX
ADC Name
ABBV-319
Synonyms
ABBV 319; ABBV-319; ABBV319
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Organization
AbbVie, Inc.
Drug Status
Phase 1
Indication
In total 3 Indication(s)
Chronic lymphocytic leukemia
Phase 1
Clinical Trial
Diffuse large B-cell lymphoma
Phase 1
Clinical Trial
Follicular lymphoma
Phase 1
Clinical Trial
Drug-to-Antibody Ratio
4
Structure
Antibody Name
Anti-CD19 ABBV319 IgG1 mAb
 Antibody Info 
Antigen Name
B-lymphocyte antigen CD19 (CD19)
 Antigen Info 
Payload Name
Proprietary GRM agonist
 Payload Info 
Therapeutic Target
Glucocorticoid receptor (NR3C1)
 Target Info 
Linker Name
Formyl-Ala-Ala
 Linker Info 
Conjugate Type
Random Cysteines