Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0KWKQC
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| ADC Name |
DX126-262
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| Synonyms |
DX126-262; DAC-001; DX-126-262
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| Organization |
Hangzhou DAC Biotechnology (DAC Biotech) (Originator)
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| Drug Status |
Phase 2
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| Drug-to-Antibody Ratio |
3.5~3.8
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| Structure |
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| Antibody Name |
DX-CHO9
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (HER2 ECD2); Receptor tyrosine-protein kinase erbB-2 (HER2 ECD4)
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Antigen Info | ||||
| Payload Name |
Tub114
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mal-PEG10 based linker
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Linker Info | ||||
| Conjugate Type |
Random Cysteines
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| Special Approval(s) |
Special approval (NMPA)
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The indication landscape of This ADC(2027 Update)
The clinical trial pipeline of This ADC(2027 Update)
| Indication | Phase 1 | Phase 1/2 | Phase 2 | Phase 2/3 | Phase 3 | New Drug Application | Approved | ||||
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| Breast cancer |
1 Trials
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1 Trials
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| Gastric cancer |
1 Trials
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1 Trials
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| Gastroesophageal junction adenocarcinoma |
1 Trials
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| Lung cancer |
1 Trials
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| Urothelial cancer |
1 Trials
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