Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ID: DRG0KUWOC)
| ADC Name |
Tras-4
|
|||||
|---|---|---|---|---|---|---|
| Synonyms |
Tras-4
Click to Show/Hide
|
|||||
| Organization |
MEMORIAL SLOAN KETTERING CANCER CENTER | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
|
|||||
| Drug Status |
Investigative
|
|||||
| Drug-to-Antibody Ratio |
2.7
|
|||||
| Antibody Name |
Trastuzumab
|
Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (HER2)
|
Antigen Info | ||||
| Payload Name |
US11141490B2-Tras-4-payload
|
Payload Info | ||||
| Linker Name |
Ethylmaleimide linker
|
Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
|
|||||
| Combination Type |
US11141490B2-Tras-4-linker-US11141490B2-Tras-4-payload
|
|||||