General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0KSJHH
ADC Name
ADC3-17
Synonyms
ADC3 17
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Organization
BeiGene Ltd.
Drug Status
Investigative
Indication
In total 3 Indication(s)
Breast cancer
Investigative
.
Colorectal cancer
Investigative
.
Non-small cell lung cancer
Investigative
.
Drug-to-Antibody Ratio
8
Structure
Antibody Name
Patritumab
 Antibody Info 
Antigen Name
Receptor tyrosine-protein kinase erbB-3 (HER3)
 Antigen Info 
Payload Name
ADC 3-17 payload
 Payload Info 
Therapeutic Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
ADC 3-17 linker
 Linker Info 
Conjugate Type
Random conjugation through reduced inter-chain cysteines.