General Information of This Antibody-drug Conjugate (ID: DRG0KNAHQ)
ADC Name
BL-M14D1
Synonyms
BL-M25D1; BL-M14D1
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Organization
Systimmune (Originator)
Drug Status
Phase 1
Drug-to-Antibody Ratio
8
Structure
Antibody Name
Anti-DLL3 mAb
 Antibody Info 
Antigen Name
Delta-like protein 3 (DLL3)
 Antigen Info 
Payload Name
Ed-04
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
Gly-Mal-Gly-Gly-Phe-Gly
 Linker Info 
Conjugate Type
Undisclosed
Combination Type
brengitecan
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Disease Name Phase 1 Phase 2 Phase 3 Approved
Lung cancer
2 Trials
Clinical trial identifier
NCT07080242
NCT06505824; CTR20242543
Merkel cell carcinoma
1 Trials
Clinical trial identifier
NCT07080242
Prostate cancer
1 Trials
Clinical trial identifier
NCT07080242
Unspecific solid tumor
2 Trials
Clinical trial identifier
NCT07080242
NCT06505824; CTR20242543