Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0KNAHQ
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| ADC Name |
BL-M14D1
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| Synonyms |
BL-M25D1; BL-M14D1
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| Organization |
Systimmune (Originator)
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| Drug Status |
Phase 1
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| Drug-to-Antibody Ratio |
8
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| Structure |
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| Antibody Name |
Anti-DLL3 mAb
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Antibody Info | ||||
| Antigen Name |
Delta-like protein 3 (DLL3)
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Antigen Info | ||||
| Payload Name |
Ed-04
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Gly-Mal-Gly-Gly-Phe-Gly
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Linker Info | ||||
| Conjugate Type |
Undisclosed
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| Combination Type |
brengitecan
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The indication landscape of This ADC(2027 Update)
The clinical trial pipeline of This ADC(2027 Update)
| Indication | Phase 1 | Phase 1/2 | Phase 2 | Phase 2/3 | Phase 3 | New Drug Application | Approved | |||
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| Lung cancer |
2 Trials
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| Merkel cell carcinoma |
1 Trials
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| Prostate cancer |
1 Trials
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| Unspecific solid tumor |
2 Trials
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