General Information of This Antibody-drug Conjugate (ID: DRG0JYFQF)
ADC Name
ZPC-21
Synonyms
ZPC-21; IM-1021
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Organization
Zentalis Pharmaceuticals (Originator) (No Rights);Immunome
Drug Status
Phase 1
Drug-to-Antibody Ratio
8
Antibody Name
Anti-ROR1 mAb
 Antibody Info 
Antigen Name
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (ROR1)
 Antigen Info 
Payload Name
HC74
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Random Cysteines
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Disease Name Phase 1 Phase 2 Phase 3 Approved
Unspecific hematological malignancies
1 Trials
Clinical trial identifier
NCT06823167; EUCT2025-523160-20-00
Unspecific solid tumor
1 Trials
Clinical trial identifier
NCT06823167; EUCT2025-523160-20-00