Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0JUYMY
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| ADC Name |
bsSORT1×HER2-DXd
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| Synonyms |
bsSORT1×HER2-DXd
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| Organization |
Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, School of Pharmacy, Shanghai Jiao Tong University.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
6.1
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| Antibody Name |
bsSORT1×HER2
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Antibody Info | ||||
| Antigen Name |
Programmed cell death 1 ligand 1 (CD274)
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Antigen Info | ||||
| Payload Name |
DX-8951 derivative (DXd)
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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