General Information of This Antibody-drug Conjugate (ID: DRG0JNCVK)
ADC Name
YL217
Synonyms
YL217
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Organization
MediLink Therapeutics (Originator)
Drug Status
Phase 1
Structure
Antibody Name
Anti-CDH17 antibody
 Antibody Info 
Antigen Name
Cadherin-17 (CDH17)
 Antigen Info 
Payload Name
YL0010014
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
VK*G-NHCH2-O linker
 Linker Info 
Conjugate Type
Random Cysteines
Combination Type
pelitecan
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Trial ID
NCT06859762; CTR20251946