General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0JNCVK
ADC Name
yL217
Synonyms
YL217
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Organization
MediLink Therapeutics (Originator)
Drug Status
Phase 1
Structure
Antibody Name
Anti-CDH17 antibody
 Antibody Info 
Antigen Name
Cadherin-17 (CDH17)
 Antigen Info 
Payload Name
YL0010014
 Payload Info 
Therapeutic Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
VK*G-NHCH2-O linker
 Linker Info 
Conjugate Type
Random Cysteines
Combination Type
pelitecan
The indication landscape of This ADC(2027 Update)
The clinical trial pipeline of This ADC(2027 Update)
Indication Phase 1 Phase 1/2 Phase 2 Phase 2/3 Phase 3 New Drug Application Approved
Unspecific solid tumor
1 Trials
Trial ID
NCT06859762; CTR20251946