Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0IXKOE
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| ADC Name |
RFB4-SMPT-dgA
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| Synonyms |
Anti-CD22 monoclonal antibody RFB4-ricin chain A conjugate; IgG-RFB4-SMPT-dgA; Monoclonal antibody RFB4-ricin chain A conjugate; NSC639179; NSC 639179
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| Organization |
National Cancer Institute; The University of Texas Southwestern Medical Center
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| Drug Status |
Terminated in phase 1
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| Indication |
In total 1 Indication(s)
B-cell lymphoma [ICD11:2A86]
Terminated in phase 1
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| Antibody Name |
RFB4
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Antibody Info | ||||
| Antigen Name |
B-cell receptor CD22 (CD22)
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Antigen Info | ||||
| Payload Name |
Deglycosylated ricin A-chain (dgA)
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Payload Info | ||||
| Linker Name |
Succynimidyloxycarbonyl-alpha-methyl-alpha-(2-pyridyl-dithio) toluene (SMPT)
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Linker Info | ||||
| Puchem SID | ||||||
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