General Information of This Antibody-drug Conjugate (ID: DRG0HWTRO)
ADC Name
SKB518
Synonyms
SKB518
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Organization
Kelun Biotherapeutics (Originator)
Drug Status
Phase 2
Antibody Name
Anti-PTK7 antibody
 Antibody Info 
Antigen Name
Inactive tyrosine-protein kinase 7 (PTK7)
 Antigen Info 
Payload Name
KL610348
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
Kthiol (pyrimidine-thiol) GGFG linker
 Linker Info 
Conjugate Type
Undisclosed
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Trial ID
NCT06428331; CTR20242227
1 Trials
Trial ID
CTR20260595
Lung cancer
1 Trials
Trial ID
NCT07019675; CTR20252228
Peritoneal cancer
1 Trials
Trial ID
NCT07448922
Ovarian cancer
1 Trials
Trial ID
NCT07448922
Fallopian tube cancer
1 Trials
Trial ID
NCT07448922
Endometrial cancer
1 Trials
Trial ID
NCT07448922