General Information of This Antibody-drug Conjugate (ID: DRG0HMQLM)
ADC Name
KHN922
Synonyms
KHN922
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Organization
Kanghong Pharmaceutical (Originator)
Drug Status
Phase 1/2
Drug-to-Antibody Ratio
7.5 (3.9+3.6)
Antibody Name
Patritumab
 Antibody Info 
Antigen Name
Receptor tyrosine-protein kinase erbB-3 (HER3)
 Antigen Info 
Payload Name
Exatecan+Triptolide
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)+RNA polymerase II
 Target Info 
Linker Name
Mc-PEG2-VA-PAB+DBCO-PEG4-GGFG
 Linker Info 
Conjugate Type
Random Cysteines+glycoside
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Disease Name Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Clinical trial identifier
NCT07514975; CTR20261200