Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
ADC ID |
DRG0GIEDE
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ADC Name |
Cetuximab-Val-Cit-Dox
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Synonyms |
Cetuximab vc DOX
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Drug Status |
Investigative
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Indication |
In total 1 Indication(s)
Colon cancer [ICD11:2B90]
Investigative
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Drug-to-Antibody Ratio |
5.5
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Structure | ||||||
Antibody Name |
Cetuximab
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Antibody Info | ||||
Antigen Name |
Epidermal growth factor receptor (EGFR)
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Antigen Info | ||||
Payload Name |
Doxorubicin
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Payload Info | ||||
Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
Combination Type |
MC-Val-Cit-PABC-DOX
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