Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0FPDDJ
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| ADC Name |
HER2-5 ADC
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| Synonyms |
HER2 5 ADC; HER2-5-ADC
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| Drug Status |
Investigative
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| Indication |
In total 2 Indication(s)
Acute myeloid leukaemia [ICD11:2A60]
Investigative
Chronic eosinophilic leukaemia [ICD11:2A20]
Investigative
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| Drug-to-Antibody Ratio |
6
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| Antibody Name |
Anti-HER2 7C2 mAb
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
GNE-987 (R)
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Payload Info | ||||
| Therapeutic Target |
Bromodomain-containing protein 4 (BRD4)
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Target Info | ||||
| Linker Name |
Dolaflexin polymer
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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