Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
ADC ID |
DRG0FFZVR
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ADC Name |
OMTX-503
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Synonyms |
OMTX 503; OMTX503
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Organization |
Oncomatryx Biopharma SL
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Drug Status |
Investigative
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Indication |
In total 1 Indication(s)
Ewing sarcoma [ICD11:2B52]
Investigative
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Antibody Name |
OMTX003
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Antibody Info | ||||
Antigen Name |
Endoglin (ENG)
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Antigen Info | ||||
Payload Name |
Nigrin b
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Payload Info | ||||
Therapeutic Target |
Ribosome (RB)
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Target Info | ||||
Linker Name |
Succynimidyloxycarbonyl-alpha-methyl-alpha-(2-pyridyl-dithio) toluene (SMPT)
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Linker Info | ||||
Conjugate Type |
ADC were generated by cystein-based conjugation of OMTX003 to either the ribosome-inactivating protein nigrin-b A chain (OMTX503).
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