General Information of This Antibody-drug Conjugate (ID: DRG0EWVOW)
ADC Name
IDP-001
Synonyms
IDP-001
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Organization
InduPro.
Drug Status
Investigative
Antibody Name
Undisclosed
Antigen Name
CUB domain-containing protein 1 (CDCP1); Epidermal growth factor receptor (EGFR)
 Antigen Info 
Payload Name
Monomethyl auristatin E
 Payload Info 
Payload Target
Microtubule (MT)
 Target Info 
Linker Name
Undisclosed
2027 Update
General Information of The ADMET Data Related to This ADC
Excretion
Click To Hide/Show 1 Excretion Data Related to This Level
Standard Type Value Units Description Reference
Elimination Half-Life (t1/2) h
Unlike other EGFR ADCs, IDP-001 does not engage immune effector cells and has a serum half-life of ~16 hours in mice.
[1]
References
Ref 1 IDP-001 is a potent bispecific ADC with in vivo activity against mouse xenograft tumor models expressing EGFR and CDCP1