Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0EQLRU
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|---|---|---|---|---|---|---|
| ADC Name |
h3G10.A57-h3G10.2.72 vcMMAD
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| Synonyms |
h3G10.A57 h3G10.2.72 vcMMAD
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| Organization |
Pfizer Inc.
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| Drug Status |
Investigative
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| Indication |
In total 4 Indication(s)
Adult T acute lymphoblastic leukemia [ICD11:2A90]
Investigative
Burkitt lymphoma [ICD11:2A85]
Investigative
Mature T-cell lymphoma [ICD11:2A90] [ICD11:2A90]
Investigative
Plasma cell myeloma [ICD11: 2A83]
Investigative
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| Drug-to-Antibody Ratio |
2
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| Antibody Name |
h3G10.A57-h3G10.2.72
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Antibody Info | ||||
| Antigen Name |
C-X-C chemokine receptor type 4 (CXCR4)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin D
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
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