General Information of This Antibody-drug Conjugate (ID: DRG0ELSER)
ADC Name
ALE.P02
Synonyms
ALE.P02
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Organization
Alentis Therapeutics (Originator)
Drug Status
Phase 1/2
Structure
Antibody Name
Anti-CLDN1 antibody
 Antibody Info 
Antigen Name
Claudin-1 (CLDN1)
 Antigen Info 
Payload Name
Monomethyl auristatin E
 Payload Info 
Payload Target
Microtubule (MT)
 Target Info 
Linker Name
Mc-Val-Cit-PABC
 Linker Info 
Conjugate Type
Random Cysteines
Combination Type
vedotin
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Oesophageal cancer
1 Trials
Trial ID
TWCT00004549; NCT06747585; EudraCT2024-515459-39; EUCT2024-515459-39-00
Lung cancer
1 Trials
Trial ID
TWCT00004549; NCT06747585; EudraCT2024-515459-39; EUCT2024-515459-39-00
Cervical cancer
1 Trials
Trial ID
TWCT00004549; NCT06747585; EudraCT2024-515459-39; EUCT2024-515459-39-00
Head and neck cancer
1 Trials
Trial ID
TWCT00004549; NCT06747585; EudraCT2024-515459-39; EUCT2024-515459-39-00