General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0ECBWC
ADC Name
WO2024140450A1 7-[N- (HS627-Ac-PEG2-Gly-Gly-Leu-Gly-ha-Ac), N-methoxyethyl]aminoethyl-10,11-methylenedi-6-mercaptopurine
Synonyms
7-[N- (HS627-Ac-PEG2-Gly-Gly-Leu-Gly-ha-Ac), N-methoxyethyl]aminoethyl-10,11-methylenedi-6-mercaptopurine
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Organization
Hangzhou Adcoris Biopharmacy Co., Ltd
Drug Status
Investigative
Drug-to-Antibody Ratio
7.4
Structure
Antibody Name
HS627
 Antibody Info 
Antigen Name
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
 Antigen Info 
Payload Name
Undisclosed
Therapeutic Target
Stimulator of interferon genes protein (STING1)
 Target Info 
Linker Name
Undisclosed
Conjugate Type
Random conjugation through reduced inter-chain cysteines.