Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0CUBIZ
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| ADC Name |
FI3789042T3Antibody-drug conjugate (13)
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| Synonyms |
FI3789042T3Antibody-drug conjugate (13)
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| Organization |
DAIICHI SNAKYO COMPANY,LIMITED
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
6.2
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| Antibody Name |
U1-59
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-3 (ERBB3)
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Antigen Info | ||||
| Payload Name |
Antibody-drug conjugate (12)payload
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Payload Info | ||||
| Linker Name |
Mc-Gly-Gly-Phe-Gly
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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ADC-specific functional property(2027 Update)
Binding Affinity
| Dissocation Constant (Kd) | Binding Target | Description | Reference |
|---|---|---|---|
| 2.757 nM |
Receptor tyrosine-protein kinase erbB-3 (ERBB3)
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Exhibited average binding affinity KD EQUIVALENT TO NON-CONJUGATED ANTI her3 ANTIBODY u1-59.
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[1]
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