Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ID: DRG0CLHLM)
| ADC Name |
AU2017363246B2 Conjugate85
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| Synonyms |
Conjugate85
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| Organization |
MERSANA THERAPEUTICS, INC.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
13.1
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| Antibody Name |
XMT-1535
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Antibody Info | ||||
| Antigen Name |
Sodium-dependent phosphate transport protein 2B (SLC34A2)
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Antigen Info | ||||
| Payload Name |
AU2017363246B2+Conjugate85+Payload
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Payload Info | ||||
| Linker Name |
AU2017363246B2+Conjugate85+Linker
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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2027 Update
General Information of The ADMET Data Related to This ADC
Absorption
| Standard Type | Value | Units | Description | Reference |
|---|---|---|---|---|
| Area Under the Concentration-Time Curve (AUC) | 462 | ug·hr/mL |
ADC with an AUC0 to 336 of 3- 402to718 ug·hr/mL.
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[1] |
Excretion
| Standard Type | Value | Units | Description | Reference |
|---|---|---|---|---|
| Elimination Half-Life (t1/2) | 134 | hr |
The terminal half-life is 134hr.
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[1] |