Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0CHKPL
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| ADC Name |
30kmPEG (SCAPDL1xSCACD47)-2 (Val-Cit-PAB-DEA-Dxd)
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| Synonyms |
30kmPEG (SCAPDL1xSCACD47)-2 (Val-Cit-PAB-DEA-Dxd)
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| Organization |
Shenzhen Enduring Biotech Ltd.
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| Drug Status |
Investigative
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| Structure |
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| Antibody Name |
undisclosed
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| Antigen Name |
Programmed cell death ligand 1 (PD-L1); Leukocyte surface antigen CD47 (CD47)
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Antigen Info | ||||
| Payload Name |
Active metabolite of irinotecan SN38
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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