Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0CANOW
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| ADC Name |
US11365263B2 ADC#2
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| Synonyms |
ADC#2
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| Organization |
Bifunctional cytotoxic agents containing the CTI pharmacophore
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
1.5
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| Structure |
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| Antibody Name |
Trastuzumab-H16-K222R-Hg1
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
US11365263B2 ADC#2 payload
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Payload Info | ||||
| Linker Name |
US11365263B2 ADC#3 linker
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
76
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