Linker Information
General Information of This Linker
| Linker ID |
LIN0UYMFV
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
US11365263B2 ADC#3 linker
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C28H45N7O7
|
|||||
| Isosmiles |
CC([C@H](NC([C@H](NC(C)=O)CCCCNC(C)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(C=C1)CO)=O)=O)C
|
|||||
| InChI |
InChI=1S/C28H45N7O7/c1-17(2)24(35-26(40)22(32-19(4)38)8-5-6-14-30-18(3)37)27(41)34-23(9-7-15-31-28(29)42)25(39)33-21-12-10-20(16-36)11-13-21/h10-13,17,22-24,36H,5-9,14-16H2,1-4H3,(H,30,37)(H,32,38)(H,33,39)(H,34,41)(H,35,40)(H3,29,31,42)/t22-,23+,24+/m1/s1
|
|||||
| InChIKey |
OSLNDOPBDYBCCF-SGNDLWITSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
591.71
|
Polar area
|
220.85
|
||
|
Complexity
|
1010.622967
|
xlogp Value
|
0.0026
|
|||
|
Heavy Count
|
42
|
Rot Bonds
|
18
|
|||
|
Hbond acc
|
7
|
Hbond Donor
|
8
|
|||
Each Antibody-drug Conjugate Related to This Linker