Antibody-drug Conjugate Information

General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0AZLBZ
ADC Name
LY-4052031
Synonyms
LY-4052031; LY 4052031; LY4052031
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Organization
Eli Lilly & Co.
Drug Status
Phase 1
Indication
In total 11 Indication(s)
Breast cancer
Phase 1
Clinical Trial
Cervical cancer
Phase 1
Clinical Trial
Head and neck cancer
Phase 1
Clinical Trial
Kidney cancer
Phase 1
Clinical Trial
Lung cancer
Phase 1
Clinical Trial
Oesophageal cancer
Phase 1
Clinical Trial
Ovarian cancer
Phase 1
Clinical Trial
Pancreatic cancer
Phase 1
Clinical Trial
Prostate cancer
Phase 1
Clinical Trial
Solid tumor
Phase 1
Clinical Trial
Urothelial cancer
Phase 1
Clinical Trial
Drug-to-Antibody Ratio
8
Antibody Name
A human IgG1 Fc-silent monoclonal Nectin-4 antibody
  Antibody Info 
Antigen Name
Nectin-4 (NECTIN4)
  Antigen Info 
Payload Name
LSN3889710
  Payload Info 
Therapeutic Target
DNA topoisomerase 1 (TOP1)
  Target Info 
Conjugate Type
Random Cysteines