General Information of This Antibody-drug Conjugate (ID: DRG0AUAOQ)
ADC Name
ZL-6201
Synonyms
ZL-6201
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Organization
Zai Lab (Originator);MediLink Therapeutics (Originator)
Drug Status
Phase 1
Drug-to-Antibody Ratio
8
Structure
Antibody Name
Anti-LRRC15 antibody
 Antibody Info 
Antigen Name
Leucine-rich repeat-containing protein 15 (LRRC15)
 Antigen Info 
Payload Name
YL0010014
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
VK*G-NHCH2-O linker
 Linker Info 
Conjugate Type
Random Cysteines
Combination Type
pelitecan
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Disease Name Phase 1 Phase 2 Phase 3 Approved
Sarcoma
1 Trials
Clinical trial identifier
NCT07374848
Unspecific solid tumor
1 Trials
Clinical trial identifier
NCT07374848